The blood glucose level is the primary controlling factor of insulin secretion.

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The blood glucose level is the main stimulus that triggers the release of insulin from the pancreas. Insulin helps to regulate blood sugar levels by allowing cells to take up glucose from the blood and use it for energy or storage. When blood sugar levels are high, insulin secretion increases, and when levels are low, insulin secretion decreases. Other factors, such as food intake, hormones, and physical activity, can also influence insulin secretion, but blood glucose level is the primary controlling factor.

The Blood Glucose Level Is the Primary Controlling Factor of Insulin