Which, If Any, of the Following Statements Is False

Which, if any, of the following statements is false?

A) The p53 tumor suppressor regulates the G₂-M transition in the cell cycle by inhibiting the CDK2-cyclin E complex.
B) p53 regulates the CDK2-cyclin E complex by stimulating the p21 tumor suppressor.
C) The CDK2-cyclin E complex relies on stimulation by the E2F transcription factor.
D) The RB1 protein normally binds the E2F transcription factor to prevent it working and so acts as a brake on the cell cycle