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Which, If Any, of the Following Statements Is Incorrect or Very

Question 14

Essay

Which, if any, of the following statements is incorrect or very likely to be incorrect?
a) Epigenetic dysregulation is essentially a universal feature of tumors.
b) Epigenetic dysregulation in cancer cells always arises as a result of mutation at a chromatin modifier locus.
c) There is an overall increase in DNA methylation across the genome of cancer cells but with local DNA hypomethylation at the promoters of a few hundred genes.
d) Epigenetic dysregulation may sometimes initiate tumorigenesis.

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