Concerning the Efficacy of Small Molecule Drugs, Which, If Any

Concerning the efficacy of small molecule drugs, which, if any, of the following statements is true?

A) At the level of clinical trials drugs can vary widely in how effective they are.
B) Once a drug has received regulatory approval, we can be sure that it will be effective in all patients, although some people will receive more benefit from it than others.
C) Drugs used to treat psychiatric disorders are particularly effective.
D) Stains and beta blockers that were meant to reduce the risk of heart disease are good examples of drugs that are largely ineffective.