Which, If Any, of the Following Statements Is False

Which, if any, of the following statements is false?

A) RNA interference (RNAi) is a cellular defense mechanism that is triggered by the presence in cells of unnatural double-stranded RNA, as can occur after viral infections.
B) RNAi therapy is a type of RNA-targeted therapy in which specific double-stranded RNA constructs are engineered to appear in diseased cells in order to incite the cells to destroy any RNA that contains the same sequence.
C) By destroying RNAs that are related to a specifically introduced genetic construct, artificial RNAi is effectively a type of gene-specific silencing.
D) RNAi therapy is best suited to silencing genes so as to replicate a phenotype caused by loss-of-function mutations.