With regard to affected sib pair (ASP) analysis which, if any, of the following statements is true.

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ASP analysis is particularly challenging for complex diseases where the relative risk to siblings is low, as it relies on the assumption that siblings share alleles more frequently than would be expected by chance alone. This method is less effective when the genetic contribution to disease risk is small, making it less suited for diseases with low relative risk.

With Regard to Affected Sib Pair (ASP) Analysis Which, If