With reference to imprinting disorders, which, if any, of the following statements is false?
A) About one quarter of individuals with Angelman syndrome lack a paternal chromosome 15.
B) With the exception of abnormal chromosome segregation, imprinting disorders always result from a deletion or inactivating mutation within, or spanning the imprinted gene cluster.
C) In some imprinting disorders, disease results from inappropriate biallelic expression of a gene.
D) Angelman and Prader-Willi syndrome are very different disorders but can be caused by precisely the same large deletion at 15q11-q13.

Question

Quizplus · Accepted Answer

Imprinting disorders can also result from uniparental disomy, where both copies of a chromosome are inherited from one parent instead of one from each parent.

With Reference to Imprinting Disorders, Which, If Any, of the Following