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With Reference to Aberrant Methylation of Bases Which of the Following

Question 9

Multiple Choice

With reference to aberrant methylation of bases which of the following statements, if any, is false?


A) S-adenosylmethionine donates methyl groups to a range of different molecules in cells and frequently inappropriately methylates bases in DNA.
B) Guanine is occasionally methylated to give O-6-methylguanine which base pairs with adenine rather than with cytidine.
C) In each nucleated cell, about 300-600 adenines are converted to 3-methyladenine per day.
D) 3-methyladenine can be a cytotoxic base: it distorts the double helix and that can disrupt crucial DNA-protein interactions.

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