The chemical substance responsible for localized pain and inflammation,such as the pain of sunburn,is:

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Prostaglandins are chemical substances that are released at the site of injury or inflammation, and they are responsible for producing pain and inflammation by sensitizing nerve endings to pain signals. NSAIDs (non-steroidal anti-inflammatory drugs) are medications that inhibit the production of prostaglandins, and therefore help to reduce pain and inflammation. Substance P and glutamate are neurotransmitters that are involved in the transmission of pain signals, but they are not specifically responsible for localized pain and inflammation like prostaglandins.

The Chemical Substance Responsible for Localized Pain and Inflammation,such as the Pain