The dosage levels of drugs prescribed for older adults must be adjusted to compensate for _____.

Question

The dosage levels of drugs prescribed for older adults must be adjusted to compensate for _____.​

Quizplus · Accepted Answer

As people age, the glomerular filtration rate (GFR) decreases, meaning that their kidneys are not as efficient at filtering waste products from the blood. This can cause drugs to take longer to metabolize and excrete from the body, resulting in potential toxicity. Dosage levels of drugs need to be adjusted to compensate for this decline in GFR in order to avoid adverse effects. The other options, decreased number of nephrons, loss of muscle tone in the urinary bladder, and increased incidence of incontinence, are also common age-related changes that can impact medication management, but they are not directly related to the dosage adjustments needed for renal function.

The Dosage Levels of Drugs Prescribed for Older Adults Must