Which of the Following Statements Is TRUE

Which of the following statements is TRUE?

A) The coordinated activity of the organ systems is necessary for normal function.
B) Because organ systems are so interrelated,dysfunction in one organ system can have profound effects on other systems.
C) An organism is any living thing considered as a whole whether composed of one cell such as a bacteria or trillions of cells such as a human.
D) Living things are highly organized and disruption of this organized state can lead to loss of function and death.
E) All of the above statements are true