Which Statement(s)about Diuretics Is/are True? (Select All That Apply

Which statement(s) about diuretics is/are true? (Select all that apply.)

A) A mechanism of action for the antihypertensive effects of diuretics includes volume depletion.
B) They have been shown to reduce cardiovascular morbidity associated with hypertension.
C) Thiazide diuretics are effective only if renal creatinine clearance is less than 30 mL/min.
D) Diuretics are sodium sparing.
E) Electrolytes must be evaluated periodically for patients on loop diuretics.