In 2000, the leader of al-Qaeda, Osama bin Laden, issued a fatwa calling for all Muslims to attack the historic enemies of Islam, __________.

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In 2000, Osama bin Laden issued a fatwa through al-Qaeda's website advocating for attacks against the United States and its allies, labeling them as the enemy of Islam. He specifically called for the killing of Americans, both military and civilian, and for Muslims worldwide to target American interests wherever possible. The fatwa also called for attacks on Israel and its supporters, primarily referring to Christianity and Judaism. Therefore, the best answer is E.

In 2000, the Leader of Al-Qaeda, Osama Bin Laden, Issued