You have three strains of mice: A, B, and C. You experimentally manipulate each strain and find that all three show increased secretion of molecule X. Now you perform a parabiosis experiment with the three combinations of these mice: AB, AC, and BC. You perform the same experimental manipulation as above on one mouse of each pair without directly affecting the other mouse and look for effects on the other mouse. You find no detectable effect on the unmanipulated partner in any of the combinations. What is the logical conclusion based on these results?

Question

Quizplus · Accepted Answer

The lack of effect on the unmanipulated partner in the parabiosis experiments suggests that the increased secretion of molecule X is not mediated by circulating factors such as hormones, which would be expected to affect both mice in each pair if they were the mechanism of action.

You Have Three Strains of Mice: A, B, and C