How could you increase the magnitude of inhibitory postsynaptic potentials IPSPs) generated at a synapse?

Question

Quizplus · Accepted Answer

Increasing the permeability of the cell membrane to Cl- ions will increase the magnitude of inhibitory postsynaptic potentials as Cl- ions will enter the cell and hyperpolarize the membrane, making it more difficult for the neuron to generate an action potential. Increasing the influx of calcium (choice B) would increase the likelihood of excitatory postsynaptic potentials, which is opposite of what the question is asking for. Increasing sodium-potassium pump activity (choice C) would not directly affect the magnitude of IPSPs.

How Could You Increase the Magnitude of Inhibitory Postsynaptic Potentials