What can proteomics reveal that genomics cannot?
A) the patterns of alternative splicing
B) the number of genes characteristic of a species
C) the movement of transposable elements within the genome
D) the levels of mRNAs present in a particular cell type
E) the set of proteins present within a cell or tissue type

Question

Quizplus · Accepted Answer

Proteomics can reveal the set of proteins present within a cell or tissue type, which cannot be solely predicted by genomics. While genomics can provide information on the number of genes within a genome and their sequences, it does not provide information on which of those genes are actually expressed and translated into proteins, nor does it provide information on post-translational modifications of proteins. Proteomics can also reveal the relative abundance of proteins in a particular cell type, which can give insights into cellular processes and functions. Alternative splicing patterns and mRNA levels can also be studied through proteomics, but these are not exclusive to this field and can also be studied through other techniques such as transcriptomics. Movement of transposable elements within the genome is a genomic phenomenon and would not be directly studied through proteomics.

What Can Proteomics Reveal That Genomics Cannot