Transcription would not occur at the appropriate initiation sites in E. coli if RNA polymerase is missing which of the following?
A) mRNA
B) amino acids
C) the core enzyme
D) sigma

Question

Quizplus · Accepted Answer

Sigma is responsible for recognizing and binding to the promoter region of DNA, thereby allowing RNA polymerase to initiate transcription at the appropriate site. Without sigma, RNA polymerase may bind to random sites on DNA and/or not recognize the proper promoter regions, leading to incorrect transcription initiation sites. Therefore, choice D is the correct answer.

Transcription Would Not Occur at the Appropriate Initiation Sites in E