As scientists were unraveling the mysteries associated with transcription and translation, they discovered there was not a one- to- one correspondence between nucleotide sequence of a gene and base sequence of the mRNA it codes for. They proposed the genes- in- pieces hypothesis. How can the genes- in- pieces hypothesis be explained?
A) Introns are noncoding segments of DNA that are present in the initial transcript, but are removed by splicing.
B) Several related genes are found in the genomes of humans and other animals.
C) Introns are noncoding segments of DNA that are not read or transcribed by RNA polymerase II.
D) Exons are noncoding segments of DNA that are not read or transcribed by RNA polymerase II.

Question

Quizplus · Accepted Answer

The genes-in-pieces hypothesis proposes that genes are composed of both coding and noncoding segments, called exons and introns, respectively. Introns are present in the initial transcript but are removed by splicing, leaving only the coding exons to be translated into protein.

As Scientists Were Unraveling the Mysteries Associated with Transcription and Translation