Glucose- 6- phosphate dehydrogenase deficiency G6PD) is inherited as a recessive allele of an X- linked gene in humans. A woman whose father suffered from G6PD marries a normal man. a) What proportion of their sons is expected to be G6PD? b) If the husband was not normal but was G6PD deficient, would you change your answer in part a)?

Question

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Since the woman is a carrier of the G6PD deficiency gene, she can pass the gene to half of her sons. Thus, the proportion of their sons who are expected to be G6PD deficient is 1/2. If the husband was also G6PD deficient, then all their sons would inherit the gene, so the proportion would be 100%. However, this scenario is not mentioned in the question.

Glucose- 6- Phosphate Dehydrogenase Deficiency G6PD) Is Inherited as a Recessive