Cancer- causing mutated tumour suppressor genes result from which of the following?
A) mutations in genes encoding proteins that normally inhibit progression through the cell cycle
B) mutations that cause overexpression of genes encoding proteins that normally stimulate progression through the cell cycle
C) cell- contact inhibition
D) programmed cell death

Question

Quizplus · Accepted Answer

Tumour suppressor genes are responsible for inhibiting the progression of the cell cycle and preventing the formation of tumours. When these genes undergo mutations that eliminate their ability to suppress the cell cycle, cancer can occur. Therefore, mutations in genes encoding proteins that normally inhibit progression through the cell cycle result in cancer-causing mutated tumour suppressor genes. Mutations that cause overexpression of genes encoding proteins that normally stimulate progression through the cell cycle (choice B) can also lead to cancer, but this is not specifically related to mutated tumour suppressor genes. Cell-contact inhibition (choice C) and programmed cell death (choice D) play important roles in preventing the growth of tumours, but they do not directly result in cancer-causing mutated tumour suppressor genes.

Cancer- Causing Mutated Tumour Suppressor Genes Result from Which of the Following