RNA is typically more susceptible to backbone hydrolysis than DNA because of the A) presence of simpler nucleotides. B) presence of a 2 ^' OH group. C) presence of a 3 ^' OH group. D) lack of thymine nucleotides.

Question

Quizplus · Accepted Answer

RNA contains a 2-OH group on its ribose sugar, which makes the backbone more susceptible to hydrolysis than DNA, which lacks this group. The presence of simpler nucleotides or the lack of thymine nucleotides is not directly related to the susceptibility of RNA backbone hydrolysis. Choice C is incorrect because the given sequence is not a proper notation for nucleotide composition.

RNA Is Typically More Susceptible to Backbone Hydrolysis Than DNA