Individuals with mutations of BRCA have increased incidence of cancer because of their

Question

Quizplus · Accepted Answer

BRCA proteins play a role in repairing double-strand DNA breaks, mutations in BRCA genes lead to an impaired ability to repair DNA damage, resulting in an increased risk of certain cancers, especially breast and ovarian cancer. The choice (C) states that individuals with mutations of BRCA have a decreased ability to repair double-strand DNA breaks, which is the correct explanation. A, B, and D are incorrect because they are not related to BRCA mutations.

Individuals with Mutations of BRCA Have Increased Incidence of Cancer