Glucagon-like peptide-1 (GLP-1) is a hormone peptide secreted by intestinal L cells. It is secreted in response to the nutrient detection in the small intestine. The resulting physiological response is the lowering of blood glucose levels. Which of the following is a potential mechanism for how GLP-1 causes this physiological response?
A) stimulation of glucagon release
B) stimulation of insulin release by pancreatic $\beta$ cells
C) increase in the apoptosis rate of pancreatic $\beta$ cells
D) downregulation of GLUT4

Question

Quizplus · Accepted Answer

GLP-1 stimulates insulin release by pancreatic β cells, leading to the uptake and utilization of glucose by target tissues, such as skeletal muscle and adipose tissue, resulting in the lowering of blood glucose levels.

Glucagon-Like Peptide-1 (GLP-1) Is a Hormone Peptide Secreted by Intestinal β\betaβ

Glucagon-Like Peptide-1 (GLP-1) Is a Hormone Peptide Secreted by Intestinal $\beta$