What is the expected outcome in a liver cell after exposure to insulin?
A) activation of fructose-1,6-bisphosphatase
B) allosteric inhibition of protein phosphatase 1
C) phosphorylation of phosphofructokinase-2/fructose-2,5-bisphosphatase
D) increased cytoplasmic concentration of fructose-2,6-bisphosphate

Question

Quizplus · Accepted Answer

Insulin stimulates the phosphorylation of phosphofructokinase-2/fructose-2,5-bisphosphatase by activating protein kinase B. This phosphorylation results in increased cytoplasmic concentration of fructose-2,6-bisphosphate, which is an activator of phosphofructokinase-1 and leads to increased glycolysis and glucose uptake.

What Is the Expected Outcome in a Liver Cell After