Reduced levels of __________ molecular-weight serum adiponectin in obese individuals results in __________ activation of AMPK signaling in muscle cells.
A) low; decreased
B) low; increased
C) high; decreased
D) high; increased

Question

Quizplus · Accepted Answer

Adiponectin is a hormone that is produced by fat cells. It has been shown to have anti-inflammatory and anti-diabetic effects. In obese individuals, levels of adiponectin are reduced. This reduction in adiponectin levels leads to increased activation of AMPK signaling in muscle cells. AMPK is a kinase that is involved in regulating energy metabolism. Increased activation of AMPK signaling in muscle cells leads to increased fatty acid oxidation and glucose uptake. This can help to improve insulin sensitivity and reduce the risk of developing type 2 diabetes.

Reduced Levels of __________ Molecular-Weight Serum Adiponectin in Obese Individuals