McArdle disease is due to a deficiency in muscle glycogen phosphorylase activity. The result of this deficiency is an inability to

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McArdle disease is also known as glycogen storage disease type V, and is caused by a deficiency in muscle glycogen phosphorylase activity. The primary function of glycogen phosphorylase in muscle tissue is to break down glycogen into glucose-1-phosphate, which can then be used by the muscle for energy via glycolysis. In McArdle disease, the inability to form glucose-1-phosphate leads to impaired muscle function and exercise intolerance.

McArdle Disease Is Due to a Deficiency in Muscle Glycogen α\alphaα

McArdle Disease Is Due to a Deficiency in Muscle Glycogen $\alpha$