According to the $\Delta$G $\degree$^' , which of the following exergonic reactions is most likely irreversible under normal cellular conditions and is considered to be the rate-limiting step of the citrate cycle? A) "citrate synthase" B) "fumarase" C) "isocitrate dehydrogenase" D) "$\alpha$-ketoglutarate dehydrogenase"

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The F1F1F1S1F1F1F10GF1F1F1S1F1F1F10F1F1F1S1^F1F1F10 represents the thermodynamic free energy change of each step in the citrate cycle. The reaction catalyzed by isocitrate dehydrogenase has the most negative free energy change (-24.4 kJ/mol) and is therefore the most exergonic and irreversible step. This reaction is also considered to be the rate-limiting step of the citrate cycle.

According to The Δ\DeltaΔ G °\degree° ' , Which of the Following Exergonic Reactions Is Most

According to The $\Delta$ G $\degree$ ^' , Which of the Following Exergonic Reactions Is Most