Fructose-1,6-bisphosphate is cleaved by aldolase.What is required for the reaction to proceed?
A) production of endergonic intermediate
B) substrate phosphorylation
C) cleaving of high-energy phosphate bond
D) formation of Schiff base intermediate

Question

Quizplus · Accepted Answer

Aldolase catalyzes the cleavage of fructose-1,6-bisphosphate into two three-carbon sugars. This reaction involves the formation of a Schiff base intermediate between the enzyme and the substrate, which is essential for the reaction to proceed.

Fructose-1,6-Bisphosphate Is Cleaved by Aldolase