When the regulatory subunit of PKA is bound to cAMP,
A) it dissociates into monomers.
B) the pseudosubstrate is phosphorylated.
C) it cannot bind to catalytic subunit of PKA.
D) it is part of a tetramer.

Question

Quizplus · Accepted Answer

When the regulatory subunit of PKA is bound to cAMP, it causes a conformational change that releases the catalytic subunit and allows it to phosphorylate its target proteins. Therefore, the regulatory subunit can bind to the catalytic subunit of PKA when it is bound to cAMP.

When the Regulatory Subunit of PKA Is Bound to CAMP