Phosphorylation of which of the following is necessary for the increased expression of antiapoptotic genes?
A) RIP
B) TNF receptor
C) FADD
D) IKK

Question

Quizplus · Accepted Answer

IKK (IκB kinase) phosphorylates IκB (inhibitor of κB) which leads to its degradation and allows the activation of NF-κB transcription factor. NF-κB can then upregulate the expression of antiapoptotic genes.

Phosphorylation of Which of the Following Is Necessary for the Increased