The lactose permease from E.coli and the molybdate transporter from Archaeoglobus fulgidus both
A) drive transport through the hydrolysis of ATP.
B) drive transport through the use of a concentration gradient.
C) undergo a conformational change that occurs on substrate binding.
D) contain a selectivity filter.

Question

Quizplus · Accepted Answer

Both the lactose permease from E.coli and the molybdate transporter from Archaeoglobus fulgidus undergo a conformational change upon substrate binding. The lactose permease is a primary active transporter that uses ATP hydrolysis to transport lactose across the cell membrane, whereas the molybdate transporter is a secondary active transporter that uses an ion gradient to power its transport. However, in both cases, the substrate binding induces a change in the transporter's conformation that allows it to transport the substrate across the membrane. Neither transporter contains a selectivity filter.

The Lactose Permease from E