Which technique ionizes polypeptides by releasing them from a small metallic capillary at high voltage?
A) ESI
B) MALDI
C) NMR
D) X-ray crystallography

Question

Quizplus · Accepted Answer

The technique described in the question is called electrospray ionization (ESI). This method ionizes polypeptides by spraying them through a small metallic capillary at high voltage, generating charged droplets that can be analyzed by mass spectrometry. MALDI (Matrix-assisted laser desorption/ionization), on the other hand, uses a laser to vaporize and ionize samples embedded in a matrix material. NMR (Nuclear Magnetic Resonance) and X-ray crystallography are other methods used for structural analysis, but they do not involve ionization of the sample.

Which Technique Ionizes Polypeptides by Releasing Them from a Small