A polypeptide has a high pI value.Which amino acids might comprise it?
A) arginine and lysine residues
B) aspartate and glutamate residues
C) the large nonpolar amino acids
D) a mixture of aspartate and arginine residues

Question

Quizplus · Accepted Answer

A high pI value indicates that the polypeptide is likely to be positively charged at physiological pH. The two amino acids that contribute the most to positive charge are arginine and lysine, as they have basic side chains with a pKa above 10.

A Polypeptide Has a High PI Value