Of the three proposed models of globular protein folding,which one describes formation of an initial disordered protein interior,followed next by ordering of secondary and tertiary structures?
A) mutant globule
B) hydrophobic collapse model
C) framework model
D) nucleation model

Question

Quizplus · Accepted Answer

The hydrophobic collapse model suggests that folding begins with the collapse of the protein's hydrophobic core, resulting in an initially disordered interior. The secondary and tertiary structures then form as the polar residues are forced to the surface and form stabilizing interactions with water molecules. The other models do not describe this specific sequence of events.

Of the Three Proposed Models of Globular Protein Folding,which One