Cystic fibrosis results from the misfolding of proteins that never get the chance to properly insert into the membranes of lung epithelial cells and perform their function.This is generally referred to as a __________ disease.

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Cystic fibrosis is a classic example of a loss-of-function protein folding disease because the misfolded proteins do not properly insert into the lung epithelial cell membranes and perform their normal function, ultimately leading to the disease phenotype.

Cystic Fibrosis Results from the Misfolding of Proteins That Never