Select the pathway that would lead to the activation of cytotoxic T cells.

Question

Quizplus · Accepted Answer

Activation of cytotoxic T cells occurs when a body cell becomes infected with a virus and displays a class I MHC molecule-antigen complex on its surface. This complex is recognized by a specific cytotoxic T cell receptor, which then triggers T cell activation and clonal expansion. Option A describes the activation of B cells, not cytotoxic T cells. Option C describes self-tolerance and B cell activation, but does not involve cytotoxic T cells. Option D describes activation of helper T cells and release of cytokines, but not activation of cytotoxic T cells. Option E describes activation of cytotoxic T cells, but through presentation of antigens on class II MHC molecules, which is not the usual pathway for these cells.

Select the Pathway That Would Lead to the Activation of Cytotoxic