Mouse mutations can affect an animal's appetite and eating habits.The ob gene codes for a satiety factor (being fed to capacity),the hormone leptin.The db gene product,the leptin receptor,is required to respond to the satiety factor.Leptin is a product of adipose cells.Therefore,a mouse that became very obese by eating in excess would be expected to have

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A mouse that became very obese by eating in excess would likely have a mutation in either the ob gene, which codes for leptin (the hormone responsible for signaling satiety), or the db gene, which codes for the leptin receptor necessary to respond to leptin. This is because normal function of these genes is crucial for regulating appetite and body weight, and their malfunction could lead to obesity due to unregulated eating.

Mouse Mutations Can Affect an Animal's Appetite and Eating Habits