What must happen to a newly made polypeptide before it can be secreted from a cell?

Question

Quizplus · Accepted Answer

In order for a newly made polypeptide to be secreted from a cell, it must have a signal sequence that targets it to the endoplasmic reticulum (ER). This signal sequence allows the polypeptide to be translocated across the ER membrane and into the lumen of the ER. Once inside the ER, the polypeptide can undergo further modifications and processing before being transported to the Golgi apparatus for further processing and eventual secretion from the cell. Therefore, choice B is the correct answer as the signal sequence must target the polypeptide to the ER before it can be secreted from the cell.

What Must Happen to a Newly Made Polypeptide Before It