The side chain (R group)of the amino acid serine is -CH₂-OH.The side chain of the amino acid leucine is -CH₂-CH-(CH₃)₂.Where would you expect to find these amino acids in a globular protein in aqueous solution?

Question

Quizplus · Accepted Answer

Serine has a polar hydroxyl group in its side chain, and it is therefore likely to be found on the exterior of the protein where it can interact with water molecules. Leucine, on the other hand, has a nonpolar side chain, and it is therefore likely to be found in the interior of the protein where it can interact with other nonpolar amino acids in the hydrophobic core of the protein. Therefore, the best choice is A, where Serine is on the exterior and Leucine is in the interior of the globular protein.

The Side Chain (R Group)of the Amino Acid Serine Is