A usually severe condition characterized by fatigue and progressive muscle weakness, especially of the face and throat, is:

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The condition described is myasthenia gravis, which is characterized by muscle weakness and fatigue, particularly in the face and throat muscles. Fibromyalgia does cause muscle pain and fatigue, but not typically weakness or issues with specific muscle groups. Muscular dystrophy is a genetic condition that leads to progressive muscle weakness and wasting, but does not commonly affect the face and throat muscles. Achondroplasia is a type of dwarfism caused by a genetic mutation, and does not involve muscle weakness.

A Usually Severe Condition Characterized by Fatigue and Progressive Muscle