Which of the following occurred amid the economic depression and created the greatest political debate of the nineteenth century, scaring Thomas Jefferson "like a firebell in the night"?

Question

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The Missouri Compromise of 1820, which dealt with the issue of slavery's expansion into new territories, was a major political debate that alarmed Thomas Jefferson, who famously described it as a "firebell in the night," indicating his fear of the potential for national division.

Which of the Following Occurred Amid the Economic Depression and Created