Recent evidence suggests that ketamine acts as a noncompetitive antagonist of the NMDA receptor.As such,it most closely resembles the action of the psychedelic:

Question

Quizplus · Accepted Answer

Ketamine's noncompetitive antagonism of the NMDA receptor is most similar to the action of angel dust, also known as PCP (phencyclidine). Both substances block the activity of the receptor, leading to altered perception and dissociative effects. Ecstasy (MDMA) works primarily on serotonin neurotransmission, mescaline primarily affects the activity of the serotonin 5HT2a receptor, and scopolamine is primarily an antagonist of the muscarinic acetylcholine receptor. None of these mechanisms are similar to ketamine's antagonism of the NMDA receptor.

Recent Evidence Suggests That Ketamine Acts as a Noncompetitive Antagonist