The existence of a nociceptin (NOP)receptor has been questioned because it does not respond to:
A)$\beta$-endorphin.
B)dynorphin-A.
C)dynorphin-B.
D)naloxone.

Question

Quizplus · Accepted Answer

Naloxone is a drug that specifically blocks the activity of opioid receptors, including mu, delta, and kappa receptors. Since the nociceptin (NOP) receptor is not affected by naloxone, this suggests that it is not an opioid receptor and may have a different mechanism of action. The other choices (A, B, and C) are opioid peptides that bind to mu, delta, and kappa receptors, respectively, and are not expected to activate the NOP receptor.

The Existence of a Nociceptin (NOP)receptor Has Been Questioned Because β\betaβ

The Existence of a Nociceptin (NOP)receptor Has Been Questioned Because $\beta$