Compared with a pure agonist,a mixed agonist-antagonist in drug-naive subjects has:
A)no effect.
B)effects opposite to the agonist.
C)lower efficacy.
D)higher efficacy.

Question

Quizplus · Accepted Answer

A mixed agonist-antagonist has lower efficacy compared with a pure agonist as it has both agonistic and antagonistic properties at the same receptor. Therefore, it may produce some effects similar to the pure agonist, but to a lesser extent.

Compared with a Pure Agonist,a Mixed Agonist-Antagonist in Drug-Naive Subjects