Even though DNA polymerase has a proofreading function, it still introduces errors in the newly synthesized strand at a rate of 1 per 10⁷ nucleotides.To what degree does the mismatch repair system decrease the error rate arising from DNA replication?

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Quizplus · Accepted Answer

The mismatch repair system significantly decreases the error rate arising from DNA replication by approximately 100-fold, further enhancing the fidelity of DNA replication beyond the proofreading capability of DNA polymerase.

Even Though DNA Polymerase Has a Proofreading Function, It Still