Which of the Following Statements About Nucleosomes Is TRUE

Which of the following statements about nucleosomes is TRUE?

A) Nucleosomes activate transcription when bound to the promoter.
B) Although RNA polymerase can access DNA packed within nucleosomes, the general transcription factors and transcriptional regulators cannot.
C) Histone acetyltransferases affect transcription by both altering chromatin structure to allow accessibility to the DNA and by adding acetyl groups to histones that can bind proteins that promote transcription.
D) Histone deacetylases remove lysines from histone tails.