Step 3 in glycolysis requires the activity of phosphofructokinase to convert fructose 6-phosphate into fructose 1,6-bisphosphate.Which of the following molecules is an allosteric inhibitor of this enzyme?

Question

Quizplus · Accepted Answer

ATP is an allosteric inhibitor of phosphofructokinase, meaning that when ATP levels are high, it will bind to the enzyme and inhibit its activity, slowing down glycolysis. Conversely, ADP and AMP can serve as activators of phosphofructokinase, signaling low energy levels and stimulating glycolysis to generate more ATP. P_i is not a known molecule and therefore cannot be the answer.

Step 3 in Glycolysis Requires the Activity of Phosphofructokinase to Convert