Which of the Following Statements Is TRUE

Which of the following statements is TRUE?

A) The signal sequences on mitochondrial proteins are usually at the C-terminus.
B) Most mitochondrial proteins are not imported from the cytosol but are synthesized inside the mitochondria.
C) Chaperone proteins in the mitochondria facilitate the movement of proteins across the outer and inner mitochondrial membranes.
D) Mitochondrial proteins cross the membrane in their native, folded state.