You are interested in Fuzzy, a soluble protein that functions within the ER lumen.Given that information, which of the following statements must be TRUE?

Question

Quizplus · Accepted Answer

The signal sequence of a protein destined for the ER lumen, like Fuzzy, is cleaved off by signal peptidase once the protein is translocated into the ER. This cleaved signal peptide is then ejected into the ER membrane and subsequently degraded, which is a standard process for proteins entering the secretory pathway.

You Are Interested in Fuzzy, a Soluble Protein That Functions