Your friend has just joined a lab that studies vesicle budding from the Golgi and has been given a cell line that does not form mature vesicles.He wants to start designing some experiments but was not listening carefully when he was told about the molecular defect of this cell line.He is too embarrassed to ask and comes to you for help.He does recall that this cell line forms coated pits but vesicle budding and the removal of coat proteins don't happen.Which of the following proteins might be lacking in this cell line?

Question

Quizplus · Accepted Answer

Dynamin is involved in the pinching off of vesicles from the membrane, a crucial step in vesicle budding. If dynamin is lacking, vesicles can form coated pits but cannot bud off completely or remove their coat proteins.

Your Friend Has Just Joined a Lab That Studies Vesicle